G21A (p.Gly21Ala) variant of F10 (Coagulation factor X)
G21A (p.Gly21Ala) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G21A (p.Gly21Ala) variant details
- p.Gly21Ala
- ExAC rs757309231
- TOPMed rs757309231
- gnomAD rs757309231
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.20
- CADD 10.50
- PolyPhen-2 0.01
- SIFT 0.58
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available