F44L (p.Phe44Leu) variant of F10 (Coagulation factor X)
F44L (p.Phe44Leu) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
F44L (p.Phe44Leu) variant details
- p.Phe44Leu
- ExAC rs768578499
- gnomAD rs768578499
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.32
- CADD 1.25
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available