E60K (p.Glu60Lys) variant of F10 (Coagulation factor X)
E60K (p.Glu60Lys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
E60K (p.Glu60Lys) variant details
- p.Glu60Lys
- ExAC rs749713392
- gnomAD rs749713392
- Missense
- Variant Prioritization Score for Impact Estimate 0.807
- REVEL 0.87
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available