E59A (p.Glu59Ala) variant of F10 (Coagulation factor X)
E59A (p.Glu59Ala) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
E59A (p.Glu59Ala) variant details
- p.Glu59Ala
- ExAC rs778379668
- gnomAD rs778379668
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.94
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available