E56K (p.Glu56Lys) variant of F10 (Coagulation factor X)
E56K (p.Glu56Lys) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
E56K (p.Glu56Lys) variant details
- p.Glu56Lys
- ExAC rs756615469
- gnomAD rs756615469
- Missense
- Variant Prioritization Score for Impact Estimate 0.82
- REVEL 0.90
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available