E22G (p.Glu22Gly) variant of F10 (Coagulation factor X)
E22G (p.Glu22Gly) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
E22G (p.Glu22Gly) variant details
- p.Glu22Gly
- ExAC rs778995263
- TOPMed rs778995263
- gnomAD rs778995263
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.19
- CADD 7.83
- PolyPhen-2 0.00
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 3.1e-05)
- Structural context available