C62S (p.Cys62Ser) variant of F10 (Coagulation factor X)
C62S (p.Cys62Ser) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
C62S (p.Cys62Ser) variant details
- p.Cys62Ser
- ExAC rs746726549
- gnomAD rs746726549
- Missense
- Variant Prioritization Score for Impact Estimate 0.754
- REVEL 0.88
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available