C57Y (p.Cys57Tyr) variant of F10 (Coagulation factor X)
C57Y (p.Cys57Tyr) in F10 (Coagulation factor X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
C57Y (p.Cys57Tyr) variant details
- p.Cys57Tyr
- TOPMed rs1338921795
- Missense
- Variant Prioritization Score for Impact Estimate 0.808
- REVEL 0.88
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available