P140S (p.Pro140Ser) variant of ETV5 (ETS translocation variant 5)
P140S (p.Pro140Ser) in ETV5 (ETS translocation variant 5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data.
P140S (p.Pro140Ser) variant details
- p.Pro140Ser
- rs971551407
- NCI-TCGA Cosmic COSV1001
- cosmic curated COSV10011
- TOPMed rs971551407
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.25
- CADD 23.80
- PolyPhen-2 0.87
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 7.3e-05)