T6T (p.Thr6Thr) variant of EGFR (Epidermal growth factor receptor)
T6T (p.Thr6Thr) in EGFR (Epidermal growth factor receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T6T (p.Thr6Thr) variant details
- p.Thr6Thr
- rs775964175
- gnomAD 7-55019295-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.109
- CADD 4.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Dabrafenib and Cetuximab HT-29 cells, base editing z-scores (predicted consequen: score 0.854
- Literature evidence available