S22S (p.Ser22Ser) variant of EGFR (Epidermal growth factor receptor)
S22S (p.Ser22Ser) in EGFR (Epidermal growth factor receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S22S (p.Ser22Ser) variant details
- p.Ser22Ser
- rs2128853494
- gnomAD 7-55019343-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.164
- CADD 11.70
- Population evidence available
- Structural context available
- Dabrafenib and Cetuximab HT-29 cells, base editing z-scores (predicted consequen: score -0.0683
- Literature evidence available