P20T (p.Pro20Thr) variant of EGFR (Epidermal growth factor receptor)
P20T (p.Pro20Thr) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P20T (p.Pro20Thr) variant details
- p.Pro20Thr
- Ensembl rs2128853462
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.09
- MetaLR 0.24
- MetaSVM -0.93
- CADD 8.50
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available