L25P (p.Leu25Pro) variant of EGFR (Epidermal growth factor receptor)
L25P (p.Leu25Pro) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L25P (p.Leu25Pro) variant details
- p.Leu25Pro
- gnomAD 7-55019351-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.20
- MetaLR 0.33
- MetaSVM -0.72
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available