L25M (p.Leu25Met) variant of EGFR (Epidermal growth factor receptor)
L25M (p.Leu25Met) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- Ensembl rs2128853521
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.14
- MetaLR 0.33
- MetaSVM -0.77
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 0.25
- Population evidence available
- Structural context available