L18P (p.Leu18Pro) variant of EGFR (Epidermal growth factor receptor)
L18P (p.Leu18Pro) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- Ensembl rs2128853447
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.48
- MetaLR 0.29
- MetaSVM -0.80
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available