L15P (p.Leu15Pro) variant of EGFR (Epidermal growth factor receptor)
L15P (p.Leu15Pro) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- gnomAD 7-55019321-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.65
- MetaLR 0.65
- MetaSVM -0.15
- CADD 25.90
- PolyPhen-2 0.99
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available