L14M (p.Leu14Met) variant of EGFR (Epidermal growth factor receptor)
L14M (p.Leu14Met) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L14M (p.Leu14Met) variant details
- p.Leu14Met
- gnomAD 7-55019317-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.28
- MetaLR 0.50
- MetaSVM -0.32
- CADD 21.20
- PolyPhen-2 0.22
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available