L11P (p.Leu11Pro) variant of EGFR (Epidermal growth factor receptor)
L11P (p.Leu11Pro) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- TOPMed rs1786369861
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.55
- MetaLR 0.58
- MetaSVM -0.36
- CADD 22.60
- PolyPhen-2 0.37
- SIFT 0.20
- Most common in the East Asian population (allele frequency 3.2e-05)
- Structural context available