L11I (p.Leu11Ile) variant of EGFR (Epidermal growth factor receptor)
L11I (p.Leu11Ile) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L11I (p.Leu11Ile) variant details
- p.Leu11Ile
- gnomAD 7-55019308-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.16
- MetaLR 0.32
- MetaSVM -0.73
- CADD 7.53
- PolyPhen-2 0.01
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available