K28R (p.Lys28Arg) variant of EGFR (Epidermal growth factor receptor)
K28R (p.Lys28Arg) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K28R (p.Lys28Arg) variant details
- p.Lys28Arg
- Ensembl rs2128853543
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.16
- MetaLR 0.31
- MetaSVM -0.76
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.75
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available