K28N (p.Lys28Asn) variant of EGFR (Epidermal growth factor receptor)
K28N (p.Lys28Asn) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K28N (p.Lys28Asn) variant details
- p.Lys28Asn
- gnomAD 7-55019361-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.23
- MetaLR 0.41
- MetaSVM -0.23
- CADD 23.50
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 3.6e-05)
- Structural context available
- Literature evidence available