K28M (p.Lys28Met) variant of EGFR (Epidermal growth factor receptor)
K28M (p.Lys28Met) in EGFR (Epidermal growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
K28M (p.Lys28Met) variant details
- p.Lys28Met
- gnomAD 7-55019360-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.41
- MetaLR 0.53
- MetaSVM -0.11
- CADD 25.70
- PolyPhen-2 0.20
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available