A10S (p.Ala10Ser) variant of EGFR (Epidermal growth factor receptor)
A10S (p.Ala10Ser) in EGFR (Epidermal growth factor receptor) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- Ensembl rs2128853375
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.14
- MetaLR 0.32
- MetaSVM -0.87
- CADD 7.08
- PolyPhen-2 0.01
- SIFT 0.64
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Population evidence available
- Structural context available