V15I (p.Val15Ile) variant of DNMT1 (P26358)
V15I (p.Val15Ile) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
V15I (p.Val15Ile) variant details
- p.Val15Ile
- ExAC rs769897113
- TOPMed rs769897113
- gnomAD rs769897113
- Missense
- Variant Prioritization Score for Impact Estimate 0.082
- REVEL 0.03
- CADD 12.20
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available