V15F (p.Val15Phe) variant of DNMT1 (P26358)
V15F (p.Val15Phe) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V15F (p.Val15Phe) variant details
- p.Val15Phe
- ExAC rs769897113
- TOPMed rs769897113
- gnomAD rs769897113
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.06
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available