S91F (p.Ser91Phe) variant of DNMT1 (P26358)
S91F (p.Ser91Phe) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S91F (p.Ser91Phe) variant details
- p.Ser91Phe
- TOPMed rs1268674999
- cosmic curated COSV10886
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.26
- CADD 23.40
- PolyPhen-2 0.80
- SIFT 0.16
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available