S84Y (p.Ser84Tyr) variant of DNMT1 (P26358)
S84Y (p.Ser84Tyr) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
S84Y (p.Ser84Tyr) variant details
- p.Ser84Tyr
- cosmic curated COSV10610
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.18
- CADD 26.30
- PolyPhen-2 0.88
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available