S127G (p.Ser127Gly) variant of DNMT1 (P26358)
S127G (p.Ser127Gly) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S127G (p.Ser127Gly) variant details
- p.Ser127Gly
- gnomAD rs2039023676
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.04
- CADD 9.03
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available