P128R (p.Pro128Arg) variant of DNMT1 (P26358)
P128R (p.Pro128Arg) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P128R (p.Pro128Arg) variant details
- p.Pro128Arg
- gnomAD rs1425787169
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.16
- CADD 16.40
- PolyPhen-2 0.37
- SIFT 0.07
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available