P128L (p.Pro128Leu) variant of DNMT1 (P26358)
P128L (p.Pro128Leu) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P128L (p.Pro128Leu) variant details
- p.Pro128Leu
- gnomAD rs1425787169
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.14
- CADD 16.60
- PolyPhen-2 0.15
- SIFT 0.07
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available