P11S (p.Pro11Ser) variant of DNMT1 (P26358)
P11S (p.Pro11Ser) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- cosmic curated COSV61579
- gnomAD rs1216341078
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.07
- AlphaMissense 0.14
- MetaLR 0.04
- MetaSVM -1.02
- CADD 23.60
- PolyPhen-2 0.30
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available