N104D (p.Asn104Asp) variant of DNMT1 (P26358)
N104D (p.Asn104Asp) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
N104D (p.Asn104Asp) variant details
- p.Asn104Asp
- gnomAD rs1170262960
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.14
- CADD 24.80
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available