G95S (p.Gly95Ser) variant of DNMT1 (P26358)
G95S (p.Gly95Ser) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G95S (p.Gly95Ser) variant details
- p.Gly95Ser
- TOPMed rs2039026843
- gnomAD rs2039026843
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.22
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available