G121E (p.Gly121Glu) variant of DNMT1 (P26358)
G121E (p.Gly121Glu) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
G121E (p.Gly121Glu) variant details
- p.Gly121Glu
- gnomAD rs1397430053
- Missense
- Variant Prioritization Score for Impact Estimate 0.0525
- REVEL 0.03
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available