A14T (p.Ala14Thr) variant of DNMT1 (P26358)
A14T (p.Ala14Thr) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A14T (p.Ala14Thr) variant details
- p.Ala14Thr
- Ensembl rs2039375350
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.13
- CADD 24.80
- PolyPhen-2 0.99
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available