A113G (p.Ala113Gly) variant of DNMT1 (P26358)
A113G (p.Ala113Gly) in DNMT1 (P26358) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A113G (p.Ala113Gly) variant details
- p.Ala113Gly
- ExAC rs762241565
- gnomAD rs762241565
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.01
- CADD 5.46
- PolyPhen-2 0.03
- SIFT 0.49
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available