L29F (p.Leu29Phe) variant of DNM1 (Dynamin-1)
L29F (p.Leu29Phe) in DNM1 (Dynamin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L29F (p.Leu29Phe) variant details
- p.Leu29Phe
- ExAC rs750933399
- gnomAD rs750933399
- Missense
- Variant Prioritization Score for Impact Estimate 0.647
- REVEL 0.71
- CADD 24.20
- PolyPhen-2 0.92
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available