D8N (p.Asp8Asn) variant of DNM1 (Dynamin-1)
D8N (p.Asp8Asn) in DNM1 (Dynamin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
D8N (p.Asp8Asn) variant details
- p.Asp8Asn
- gnomAD rs1444303998
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.35
- CADD 24.40
- PolyPhen-2 0.08
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available