V33M (p.Val33Met) variant of DDC (P20711)
V33M (p.Val33Met) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
V33M (p.Val33Met) variant details
- p.Val33Met
- cosmic curated COSV10817
- ExAC rs200593672
- TOPMed rs200593672
- gnomAD rs200593672
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.27
- CADD 24.90
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available