V33L (p.Val33Leu) variant of DDC (P20711)
V33L (p.Val33Leu) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
V33L (p.Val33Leu) variant details
- p.Val33Leu
- ExAC rs200593672
- TOPMed rs200593672
- gnomAD rs200593672
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.29
- CADD 22.80
- PolyPhen-2 0.14
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available