S4T (p.Ser4Thr) variant of DDC (P20711)
S4T (p.Ser4Thr) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S4T (p.Ser4Thr) variant details
- p.Ser4Thr
- ExAC rs769697130
- TOPMed rs769697130
- gnomAD rs769697130
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.07
- CADD 5.24
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available