P66R (p.Pro66Arg) variant of DDC (P20711)
P66R (p.Pro66Arg) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
P66R (p.Pro66Arg) variant details
- p.Pro66Arg
- Ensembl rs1563044251
- Missense
- Variant Prioritization Score for Impact Estimate 0.693
- REVEL 0.63
- CADD 25.80
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available