N19S (p.Asn19Ser) variant of DDC (P20711)
N19S (p.Asn19Ser) in DDC (P20711) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N19S (p.Asn19Ser) variant details
- p.Asn19Ser
- NCI-TCGA Cosmic COSV6356
- cosmic curated COSV63563
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.09
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available