M65K (p.Met65Lys) variant of DDC (P20711)
M65K (p.Met65Lys) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
M65K (p.Met65Lys) variant details
- p.Met65Lys
- TOPMed rs951364390
- Missense
- Variant Prioritization Score for Impact Estimate 0.667
- REVEL 0.69
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available