M21T (p.Met21Thr) variant of DDC (P20711)
M21T (p.Met21Thr) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
M21T (p.Met21Thr) variant details
- p.Met21Thr
- gnomAD rs564229359
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.18
- CADD 22.80
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the HGDP:YAKUT population (allele frequency 0.02)
- Structural context available