I64T (p.Ile64Thr) variant of DDC (P20711)
I64T (p.Ile64Thr) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
I64T (p.Ile64Thr) variant details
- p.Ile64Thr
- TOPMed rs2044716414
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.68
- CADD 26.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available