F6L (p.Phe6Leu) variant of DDC (P20711)
F6L (p.Phe6Leu) in DDC (P20711) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
F6L (p.Phe6Leu) variant details
- p.Phe6Leu
- gnomAD rs1287025678
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.46
- CADD 24.10
- PolyPhen-2 0.69
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available