Y42C (p.Tyr42Cys) variant of CYP4F2 (Cytochrome P450 4F2)
Y42C (p.Tyr42Cys) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
Y42C (p.Tyr42Cys) variant details
- p.Tyr42Cys
- TOPMed rs2089454743
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.37
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available