W8C (p.Trp8Cys) variant of CYP4F2 (Cytochrome P450 4F2)
W8C (p.Trp8Cys) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
W8C (p.Trp8Cys) variant details
- p.Trp8Cys
- TOPMed rs1172572612
- gnomAD rs1172572612
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.45
- CADD 22.50
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available