W59S (p.Trp59Ser) variant of CYP4F2 (Cytochrome P450 4F2)
W59S (p.Trp59Ser) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
W59S (p.Trp59Ser) variant details
- p.Trp59Ser
- ExAC rs753256315
- gnomAD rs753256315
- Missense
- Variant Prioritization Score for Impact Estimate 0.555
- REVEL 0.73
- CADD 24.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the HGDP:KALASH population (allele frequency 0.12)
- Structural context available